Immediate outcomes of transcatheter aortic valve implantation in patients with horizontal aorta

Background: Transcatheter aortic valve implantation (TAVI) is an effective and safe procedure for severe stenosis. Increased root angulation important anatomical feature that may cause technical difficulties negatively affect immediate long-term outcomes.Objective: To evaluate outcomes of TAVI in patients with increased angulation.Methods: Our retrospective single-center study included 412 stenosis who underwent using self-expanding bioprostheses from 2015 to 2022. Patients ≥ 49° were group 1 (n = 200), those < comprised 2 212).Results: The mean age the was 75.2 ± 7.2 years. In a subgroup first-generation CoreValve prosthesis angle, we observed moderate regurgitation significantly more often (7.4% vs 0.0%, P .010) success less (90.1% 98.9%, compared similar angle. subgroups Evolute R ACURATE neo prostheses, there no significant differences terms mentioned parameters. Independent predictors failure angle [OR each degree increase: 0.44, 95% CI: 0.30-0.63, .001], postdilation [OR: 5.0, 1.33-20.00, .074], indexed mass left ventricular myocardium 1.02, 1.01-1.03, .003], higher relative annulus every mm decrease depth: .001].Conclusion: affected only prostheses. postdilation, myocardium, annulus. Received 9 January 2023. Revised 10 May Accepted 30 Funding: did not have sponsorship. Conflict interest: authors declare conflict interest. Contribution authorsConception design: A.A. Baranov, O.V. Krestyaninov, D.A. Khelimskii, A.G. BadoianData collection analysis: BadoianStatistical BadoianDrafting article: Badoian, S.N. Manukian, A.Yu. Tsydenova, M.A. MakhmudovCritical revision MakhmudovFinal approval version be published: Makhmudov